Institute: ONC | Component: 2 | Unit: 5 | Lecture: c | Slide: 13
Institute:Office of National Coordinator (ONC) Workforce Training Curriculum
Component:The Culture of Health Care
Unit:Evidence-Based Practice
Lecture:Phrasing the clinical question Interventions
Slide content:Examples of RCTs Continued Eradication of H. pylori to prevent recurrence of gastric cancer ( Fukase et al., 2008) H. pylori is bacteria associated with peptic ulcer disease When eradicated with antibiotics in patients with cancer of stomach, recurrence of cancer is less likely to occur Relative risk reduction = 66% 13
Slide notes:An example of an RCT showing benefit for an intervention comes from a study of whether eradication of Helicobacter pylori [ hel - i - koh -back- ter pie- lor - ee ] bacteria from the stomach of individuals with gastric cancer (cancer in the stomach) reduces recurrence of the disease. This eradication was done with a combination of antibiotics and resulted in a relative risk reduction of sixty-six percent, or a two-thirds reduction, in the number of cases of recurrence. 13